Phytochemical Analysis and Apoptosis-Inducing Anticancer Activity of Buddleja polystachia Leaf Extract against HeLa Cell Lines

Key Points

• This research aims to evaluate the anticancer properties of Buddleja polystachia leaf extract on cervical cancer cells.
• Conducted phytochemical analysis of Buddleja polystachia leaf extract.
• Assessed the extract's effects on HeLa cervical cancer cell lines.
• Investigated the activation of the p53-mediated intrinsic apoptotic pathway.
• Buddleja polystachia leaf extract significantly induced apoptosis in HeLa cells.
• The extract activated the p53-mediated intrinsic apoptotic pathway.
• It shows potential as an alternative therapeutic agent for cervical cancer with limited harm to normal cells.

Abstract