What question did this study set out to answer?

This research aims to redefine lung injury risk in ventilated patients by integrating mechanical power parameters.

April 10, 2026Open Access

Power, Duration, and Compliance: Reframing Risk of Ventilatory-Induced Lung Injury With the Risk-Adjusted Mechanical-Power Score

Key Points

This research aims to redefine lung injury risk in ventilated patients by integrating mechanical power parameters.
Analyzed the interaction between power intensity, duration, and respiratory compliance.
Developed a risk-adjusted mechanical power score to assess ventilatory impacts.
Suggested prospective validation for individualizing ventilator settings.
Identified a dynamic interplay between power, duration, and compliance affecting lung injury risk.
Proposed the risk-adjusted score as a clinically useful tool for ventilator management.

Abstract

A single "safe" MP threshold is insufficient for guiding ventilation; the risk of lung injury is governed by a dynamic interplay of power intensity, duration, and the patient's respiratory compliance. The risk-adjusted MP score unifies these factors into a time-varying, clinically interpretable metric that warrants prospective validation for personalized ventilator management.

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Discussion

Authors

Lada Lijović

Paul Hilders

Tomislav Radočaj

Journals

Critical Care Medicine

Actions

Institutions

Vrije Universiteit Amsterdam

Amsterdam University Medical Centers

Amsterdam Neuroscience

References and Citations

Connected Papers

Building similarity graph...

Analyzing shared references across papers

Power, Duration, and Compliance: Reframing Risk of Ventilatory-Induced Lung Injury With the Risk-Adjusted Mechanical-Power Score

Key Points

Abstract

Citation Network

Connected Papers

Discussion

Authors

Journals

Actions

Institutions

References and Citations

Citation Network

Connected Papers

Discussion

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