Does 18F-FAPI PET/CT imaging detect early fibro-inflammatory activity predictive of coronary restenosis?
49-year-old woman with chronic total occlusion of the proximal left anterior descending (LAD) artery (n=1)
18F-FAPI PET/CT imaging at baseline, 6 months, and 1 year
Detection of fibro-inflammatory activity predictive of in-stent restenosissurrogate
18F-FAPI PET/CT imaging may serve as a novel non-invasive tool to detect early fibro-inflammatory activity predictive of coronary in-stent restenosis.
A 49-year-old woman with chronic total occlusion of the proximal left anterior descending (LAD) artery underwent a baseline 18F-FAPI PET/CT, and showed no abnormal uptake in the coronary artery. New focal 18F-FAPI activity appeared at the LAD stent ostium at 6 months and progressed by 1 year, preceding angiographically confirmed in-stent restenosis. This case demonstrates that 18F-FAPI imaging may detect early fibro-inflammatory activity predictive of restenosis.
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Xiao-Ying Xi
Shengwen Yang
Bin Tu
Clinical Nuclear Medicine
Beijing Chao-Yang Hospital
Beijing Chaoyang Emergency Medical Center
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Xi et al. (Thu,) studied this question.
www.synapsesocial.com/papers/69d894ec6c1944d70ce05db2 — DOI: https://doi.org/10.1097/rlu.0000000000006432