Impact of Real Time, Flash and Retrospective Continuous Glucose Monitoring on Feto‐Maternal Outcomes in Women With Gestational Diabetes and Pre‐Gestational Diabetes: A Systematic Review and Meta‐Analysis With Trial Sequential Analysis of Randomized Controlled Trials

Key Points

• This research aims to evaluate the effects of different continuous glucose monitoring methods on outcomes for mothers and babies with diabetes during pregnancy.
• Conducted a systematic review and meta-analysis of randomized controlled trials.
• Analyzed the impact of real-time, flash, and retrospective CGM on feto-maternal outcomes.
• Performed Trial Sequential Analysis to assess the robustness of findings.
• Real-time continuous glucose monitoring likely reduces admissions to the neonatal intensive care unit (NICU) with moderate confidence.
• Other CGM models showed mostly neutral effects on feto-maternal outcomes.
• Current evidence is limited, indicating the need for larger future randomized controlled trials.

Abstract