What question did this study set out to answer?

To assess the relationship between medications for substance use disorders and the risk of posterior non-infectious uveitis.

April 10, 2026

Risk of Non-Infectious Uveitis Associated with Medications for Substance Use Disorders

Key Points

To assess the relationship between medications for substance use disorders and the risk of posterior non-infectious uveitis.
Analyzed prescription patterns of medications for substance use disorders.
Compared risk of uveitis against selective serotonin reuptake inhibitors (SSRIs).
Considered a real-world patient population.
Mild increased risk of posterior non-infectious uveitis associated with medications for substance use disorders.
No increase in risk in low inflammatory risk settings compared to SSRIs.
Suggests need for ophthalmologic monitoring for patients on these medications.

Abstract

MAT prescriptions may be associated with a mild increased risk of posterior NIU in the real-world setting, but not the low inflammatory risk setting, compared with SSRIs. These findings suggest a potential benefit of ophthalmologic monitoring in patients prescribed MAT, although institutional studies reviewing each medication are necessary to confirm these results.

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Discussion

Authors

Matthew J. Schulgit

Ashley Hailer

Margaret G. Miller

Journals

Ocular Immunology and Inflammation

Actions

Institutions

Case Western Reserve University

Cleveland Clinic

MetroHealth

References and Citations

Connected Papers

Building similarity graph...

Analyzing shared references across papers

Risk of Non-Infectious Uveitis Associated with Medications for Substance Use Disorders

Key Points

Abstract

Citation Network

Connected Papers

Discussion

Authors

Journals

Actions

Institutions

References and Citations

Citation Network

Connected Papers

Discussion

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