Most typhoon-exposed individuals with PTSD may exhibit structural alterations in brain white matter. By combining fixel-based analysis (FBA) with machine learning, this study identified diffusion markers within specific white matter tracts and demonstrated their potential diagnostic value for distinguishing PTSD from trauma-exposed controls. These findings enhance our understanding of microstructural white matter changes and their spatial distribution in PTSD and also suggest potential imaging biomarkers for its diagnosis.
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Yalin Zhang
Huijuan Chen
Rongfeng Qi
Brain and Behavior
Central South University
Soochow University
Nanjing Medical University
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Zhang et al. (Wed,) studied this question.
www.synapsesocial.com/papers/69d895206c1944d70ce0628d — DOI: https://doi.org/10.1002/brb3.71354