What question did this study set out to answer?

To determine the impact of long-acting injectable antipsychotics on readmission rates in young patients with early psychosis.

April 10, 2026

Long-Acting Injectable Antipsychotics and Time to Readmission in Early Psychosis

Key Points

To determine the impact of long-acting injectable antipsychotics on readmission rates in young patients with early psychosis.
Analyzed readmission data for young patients with early psychosis prescribed long-acting injectables.
Compared readmission rates between LAI users and non-users over one year.
Evaluated the influence of housing instability on readmission patterns.
No significant difference in 1-year readmission rates between LAI and non-LAI cohorts.
Housing instability was identified as a significant factor affecting readmission rates.
LAIs were prescribed mainly to higher-risk patients, yet outcomes were similar overall.

Abstract

For young patients with early psychosis, LAIs were preferentially prescribed to higher-risk patients but were not independently associated with reduced 1-year readmission. Comparable outcomes between groups despite greater baseline risk in the LAI cohort suggest that LAIs may partially mitigate elevated risk, though this interpretation requires prospective confirmation. Housing instability emerged as a critical determinant of readmission patterns, underscoring the need for integrated pharmacologic and social interventions in this population.

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Discussion

Authors

Caroline Wang

Sean Lynch

Chaden Noureddine

Journals

Journal of Child and Adolescent Psychopharmacology

Actions

Institutions

Columbia University

Icahn School of Medicine at Mount Sinai

Mount Sinai Hospital

References and Citations

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Building similarity graph...

Analyzing shared references across papers

Long-Acting Injectable Antipsychotics and Time to Readmission in Early Psychosis

Key Points

Abstract

Citation Network

Connected Papers

Discussion

Authors

Journals

Actions

Institutions

References and Citations

Citation Network

Connected Papers

Discussion

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