Foxq1‐Wnt5a Axis Activation in Dental Papilla Stem Cells Promotes Odontogenesis on Acellular Matrix: A Laboratory Investigation

Key Points

• This study aims to explore how the Foxq1-Wnt5a signaling pathway influences odontogenesis in dental papilla stem cells.
• Laboratory investigation of Foxq1-Wnt5a axis activation.
• Utilization of acellular dentine scaffolds for testing.
• Analysis of tubular dentine regeneration.
• Activation of Foxq1-Wnt5a significantly enhanced odontogenesis.
• Successful tubular dentine regeneration observed on acellular matrix.
• Findings suggest a synergistic effect between signaling pathways and scaffolds.

Abstract