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Umbrella review finds several ADHD treatments efficacious in short term | Synapse

April 10, 2026

Umbrella review finds several ADHD treatments efficacious in short term

Key Points

This research aims to evaluate the short-term efficacy of various medication treatments for ADHD in youths.
Conducted an umbrella review of 47 meta-analytic reports
Analyzed short-term effect sizes of ADHD treatments
Included medications such as amphetamines and methylphenidate
Found medium to large effect sizes for several medication treatments
No strong long-term results were reported for any intervention
Efficacy noted specifically in youth populations

Abstract

An umbrella review encompassing 47 meta‐analytic reports has found medium to large effect sizes in the short term for several medication treatments for attention‐deficit hyperactivity disorder (ADHD) in youths, including amphetamines and methylphenidate. No interventions in youth or adult treatment showed strong long‐term results. The review was published online Nov. 27, 2025, in the BMJ .

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A Wed, study studied this question.

www.synapsesocial.com/papers/69d895d86c1944d70ce07016 — DOI: https://doi.org/10.1002/pu.31437

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The Brown University Psychopharmacology Update

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