Testosterone replacement therapy in older men: skeletal outcomes and fracture risk

Key Points

• To evaluate the effects of testosterone replacement therapy (TRT) on skeletal outcomes and fracture risk in older men with hypogonadism.
• Analyzed outcomes of testosterone replacement therapy in older men with confirmed hypogonadism.
• Assessed body composition and functional outcomes related to skeletal health.
• Emphasized the need for patient selection and monitoring regarding fracture risk.
• TRT improved body composition and some functional outcomes.
• TRT was not effective as a disease-modifying strategy for preventing falls or fractures.
• Recommends careful patient selection and ongoing monitoring due to regulatory warnings.

Abstract