Are serum MOTS-c levels and MOTS-c m.1382A>C polymorphism related to polycystic ovary syndrome?

Key Points

• The aim is to investigate the relationship between MOTS-c levels, its polymorphism, and polycystic ovary syndrome (PCOS).
• Comparison of serum MOTS-c levels between individuals with PCOS and healthy controls.
• Analysis of the MOTS-c m.1382A>C polymorphism.
• No significant association between the MOTS-c m.1382A>C polymorphism and PCOS.
• Serum MOTS-c levels are similar in individuals with PCOS and healthy controls.
• MOTS-c may have a minor role in the pathophysiology of PCOS.

Abstract