Osteoinductive chemically crosslinked hydrogel enables hydroxyapatite formation, enhanced by release of dexamethasone, strontium, and zinc, and exhibits antimicrobial properties

Key Points

• To evaluate the effectiveness of a chemically crosslinked hydrogel in promoting bone regeneration and its antimicrobial properties.
• Developed a chemically crosslinked hydrogel
• Tested hydrogel's ability to facilitate hydroxyapatite formation
• Assessed release of dexamethasone, strontium, and zinc
• Evaluated antimicrobial effects of the hydrogel
• Hydrogel successfully induced hydroxyapatite formation
• Release of dexamethasone, strontium, and zinc enhanced bone regeneration
• Hydrogel exhibited significant antimicrobial properties

Abstract