Implications for Sentinel Lymph Node Biopsy Omission in Patients with Early-Stage Node-Negative HR+/HER2− Breast Cancer Undergoing Mastectomy

Key Points

• To explore the implications of omitting sentinel lymph node biopsy (SLNB) in patients with early-stage node-negative breast cancer undergoing mastectomy.
• Analyzed patients with cT1N0M0 HR+/HER2- disease and negative AUS
• Compared early recurrence rates across different surgical types
• Identified impact of nodal status on radiotherapy post-mastectomy
• Early recurrence rates were found to be low irrespective of surgery type
• Omission of SLNB may not significantly affect recurrence in this patient group
• Need for further studies to solidify the rationale for SLNB omission

Abstract