Access to Cyclobutanones by a Photoredox‐Catalyzed Deoxygenation/Wolff Rearrangement/Cycloadditions Cascade Reaction

Key Points

• To develop a novel method for synthesizing cyclobutanones through a cascade reaction involving photoredox catalysis.
• Utilized visible-light catalysis for the reaction sequence
• Conducted deoxygenation followed by Wolff rearrangement and cycloadditions
• Examined reactions with various electron-donating and electron-withdrawing substituents
• Successfully synthesized substituted cyclobutanones from α-diketones
• Showed compatibility with a range of substituents under mild reaction conditions
• Provided a straightforward access to these compounds

Abstract