Novel NHC-based Pd–PEPPSI complexes: synthesis, structural characterization by X-ray diffraction, biological properties, and catalytic performance in N -alkylation reactions

Key Points

• To explore the synthesis and catalytic properties of novel Pd-PEPPSI-NHC complexes for N-alkylation reactions.
• Synthesized Pd-PEPPSI-NHC complexes
• Characterized structures using X-ray diffraction
• Evaluated catalytic performance in N-alkylation of amines and alcohols
• Successfully performed N-alkylation using Pd-PEPPSI-NHC complexes
• Demonstrated effectiveness in the borrowing-hydrogen approach
• First report of this catalyst class in N-alkylation transformations

Abstract