Oral Mucositis in Oncopediatric Patients: MTX and MMP ‐1, MMP ‐8, MMP ‐13 Gene Polymorphisms

Key Points

• This research aims to determine if certain gene polymorphisms are markers for oral mucositis in pediatric cancer patients.
• Analysis of gene polymorphisms in MMP-1, MMP-8, and MMP-13.
• Assessment of oral mucositis occurrence and severity in oncopediatric patients.
• Correlation of genetic variations with mucositis susceptibility.
• Identified specific polymorphisms associated with increased risk of oral mucositis.
• Proposed that genotyping may assist in personalizing treatment plans.
• Indicated potential for reduced mucositis severity through tailored interventions.

Abstract