Photoinduced HCl-Catalyzed Acylation of N‑Heterocycles

Key Points

• To explore an electron donor-acceptor photochemical system for the regioselective acylation of nitrogen-containing heterocycles.
• Developed an EDA photochemical platform
• Utilized inexpensive HCl as a catalyst
• Focused on C(sp²)–H acylation of heterocycles
• Achieved regioselective acylation in nitrogen-containing heterocycles
• Demonstrated effectiveness using catalytic amounts of HCl
• Highlighted the potential for cost-effective chemical transformations

Abstract