What is the clinical evidence from this study?

Study design: Observational. Population: Mycoplasma pneumoniae pneumonia (n=79). Intervention: Mycoplasma pneumoniae infection vs. Healthy controls. Primary outcome: Left ventricular ejection fraction (LVEF) (95% CI -1.336 to -0.254, p=0.004).

What question did this study set out to answer?

This research aims to evaluate how Mycoplasma pneumoniae infection impacts left ventricular function in children.

April 15, 2026Open Access

Evaluation and follow-up of left ventricular function in children with Mycoplasma pneumoniae pneumonia using cardiac magnetic resonance feature tracking

Key Result

Mycoplasma pneumoniae infection significantly reduced left ventricular ejection fraction to 54.77% compared to 60.62% in healthy controls, with partial recovery observed after 3 months.

Key Points

This research aims to evaluate how Mycoplasma pneumoniae infection impacts left ventricular function in children.
Used cardiac magnetic resonance imaging to assess left ventricular function.
Measured left ventricular ejection fraction (LVEF) and myocardial strain in children with pneumonia.
Conducted follow-up assessments at three months to evaluate recovery.
LVEF and myocardial strain showed a good recovery after three months.
Some children continued to show abnormal cardiac function parameters or signs of inflammation.

Study Design

Type

Observational

Blinding

Single-blind

Multicenter

Structured PICO

How does left ventricular function recover over time in children with Mycoplasma pneumoniae pneumonia as evaluated by cardiac magnetic resonance feature tracking?

Population

Children with Mycoplasma pneumoniae pneumonia

Intervention

Cardiac magnetic resonance feature tracking

Outcome

Left ventricular function (LVEF and myocardial strain)surrogate

Cardiac magnetic resonance feature tracking demonstrates that while LVEF and myocardial strain typically recover within three months in children with Mycoplasma pneumoniae pneumonia, some subclinical abnormalities or inflammation may persist.

Limitations

Contrast-enhanced CMR imaging was not performed, preventing the assessment of myocardial fibrosis and application of the Lake Louise Criteria.
Significant drop-out rate during the follow-up period, with 31.6% of initial participants lost to follow-up.
The 3-month follow-up duration may be insufficient to fully evaluate long-term cardiac remodeling.

Abstract

Mycoplasma pneumoniae infection might affect LV function in children. The LVEF and myocardial strain generally show good recovery after three months, although some children may continue to exhibit abnormalities in other cardiac function parameters or imaging signs of cardiac inflammation.

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Discussion

Authors

Jingya Lu

Yulong Ma

Anling Xiao

Journals

Cardiology Journal

Actions

Institutions

Zhejiang Chinese Medical University

Fuyang City People's Hospital

References and Citations

Connected Papers

Building similarity graph...

Analyzing shared references across papers

Evaluation and follow-up of left ventricular function in children with Mycoplasma pneumoniae pneumonia using cardiac magnetic resonance feature tracking

Key Result

Key Points

Study Design

Structured PICO

Limitations

Abstract

Citation Network

Connected Papers

Discussion

Authors

Journals

Actions

Institutions

References and Citations

Citation Network

Connected Papers

Discussion

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