Effects of a 24-week resistance exercise program on Alzheimer’s disease brain signatures in cognitively unimpaired older adults: a secondary analysis of the AGUEDA randomized controlled trial

Key Points

• This research aims to investigate how a 24-week resistance exercise program affects brain signatures related to Alzheimer's disease in cognitively unimpaired older adults.
• Conducted a secondary analysis of the AGUEDA randomized controlled trial.
• Participants engaged in a 24-week resistance exercise program.
• Brain signatures were assessed pre- and post-intervention.
• The resistance exercise program improved cognitive function indicators in participants.
• Significant changes in brain signatures associated with Alzheimer's disease were noted after 24 weeks.

Abstract