What question did this study set out to answer?

To evaluate the effectiveness and safety of microsurgical resection for treating subependymal giant cell astrocytoma.

April 15, 2026

Microsurgical Resection of Subependymal Giant Cell Astrocytoma: Single-Center Retrospective Analysis and Meta-Analysis

Key Points

To evaluate the effectiveness and safety of microsurgical resection for treating subependymal giant cell astrocytoma.
Conducted a single-center retrospective analysis
Performed a meta-analysis of available data on SEGA surgical outcomes
Included patients without hydrocephalus in the analysis
Microsurgical resection demonstrated high safety and efficacy
Early intervention led to lower need for VPS (ventriculoperitoneal shunt)
Durable tumor control noted particularly in unilateral SEGA cases

Abstract

Microsurgical resection of SEGA is a safe and effective therapeutic option, particularly in patients without hydrocephalus. Early surgical intervention may reduce the need for VPS and long-term complications, offering a valid alternative or complement to mechanistic target of rapamycin inhibitor therapy, with durable tumor control especially in unilateral cases.

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Discussion

Authors

Luca Sartori

Lelio Guida

Stéphanie Puget

Journals

Neurosurgery

Actions

Institutions

Inserm

Université Paris Cité

Assistance Publique – Hôpitaux de Paris

References and Citations

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Building similarity graph...

Analyzing shared references across papers

Microsurgical Resection of Subependymal Giant Cell Astrocytoma: Single-Center Retrospective Analysis and Meta-Analysis

Key Points

Abstract

Citation Network

Connected Papers

Discussion

Authors

Journals

Actions

Institutions

References and Citations

Citation Network

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Discussion

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