Lysosomal dynamics in cellular remodeling and disease

Key Points

• The research aims to uncover the regulatory mechanisms involved in lysosomal regeneration and their implications for various physiological processes and diseases.
• Analyzed lysosomal dynamics in response to metabolic and developmental signals.
• Investigated the role of phospholipids in lysosomal morphology changes.
• Examined the functions of molecular machinery involved in lysosomal regulation.
• Lysosomes show significant heterogeneity and form dynamic structures for regeneration.
• Phospholipid composition critically regulates lysosomal shape changes.
• Dysfunction in lysosomal dynamics is associated with various diseases.

Abstract