Biorelevant assessment of commercial probiotics using porcine gastrointestinal fluids

Key Points

• The central aim is to evaluate the viability of probiotics using porcine gastrointestinal fluids as an alternative to human-derived or synthetic simulations.
• Established porcine gastrointestinal fluids for probiotic viability assessment
• Compared porcine fluids to synthetic and human-derived fluids
• Analyzed probiotic resilience during gastric transit
• Probiotics showed varying resilience levels in porcine fluids compared to synthetic simulations
• Findings underscore the need for enhancing probiotic delivery methods to maximize health benefits

Abstract