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We demonstrate that the AR regulates a network of DNA repair genes, providing a potential mechanism by which androgen deprivation synergizes with radiotherapy for prostate cancer.
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Polkinghorn et al. (Wed,) studied this question.
www.synapsesocial.com/papers/69df45b2de200760a8614d19 — DOI: https://doi.org/10.1158/2159-8290.cd-13-0172
William R. Polkinghorn
Joel S. Parker
Man X. Lee
Cancer Discovery
University of North Carolina at Chapel Hill
Memorial Sloan Kettering Cancer Center
Albert Einstein College of Medicine
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