Findings highlight the need for topic-aware governance: guideline-dense queries suited to retrieval-augmented generation and checklist compliance, and context-sensitive queries requiring uncertainty signaling and human oversight. This layered approach advances health informatics by defining where LLMs may substitute versus where they require verification, supporting safe and auditable integration into patient education.
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Akyüz et al. (Thu,) studied this question.
www.synapsesocial.com/papers/69e3205140886becb653f6ad — DOI: https://doi.org/10.1080/17538157.2026.2654150
Bülent Akyüz
Ilhan Sezer
Ali Nail Demir
Informatics for Health and Social Care
Akdeniz University Hospital
Applied Research Associates
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