Spread of extended-spectrum β-lactamase-producing Enterobacterales (ESBL-E) in the community living spaces of patients identified as ESBL-E carriers: impact of the housing density in an African context

Key Points

• To explore the spread of extended-spectrum β-lactamase-producing Enterobacterales in community living spaces and assess the influence of housing density.
• Conducted a geographic analysis of ESBL-E colonization in humans and animals.
• Performed genomic analysis to investigate strain diversity and potential dissemination.
• Significant colonization of ESBL-E observed in both humans and animals.
• Geographic analysis suggests human impact on animal colonization without direct transmission.
• Genomic findings indicate potential for ESBL-E dissemination over large distances.

Abstract