This review translates current evidence into a clinician-oriented framework for patient selection, prescribing, monitoring, and treatment adjustment, emphasizing initiation triggers in stalled wounds and trajectory-based reassessment every 2-4 weeks. Future work should prioritize pragmatic, well-controlled trials comparing formulations and dosing windows by wound etiology, together with biomarker-informed stratification to improve personalization, safety, and real-world uptake.
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Zilong Tan
Yi Ru
C L Zhang
Advances in Wound Care
Tongji University
Shanghai University of Traditional Chinese Medicine
Shanghai Skin Disease Hospital
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Tan et al. (Sun,) studied this question.
www.synapsesocial.com/papers/69e7143fcb99343efc98d99d — DOI: https://doi.org/10.1177/21621918261444178