Genetic analysis and clinical phenotype of pulmonary arterial hypertension in an Algerian population

Key Points

• This research aims to evaluate the genetic factors and clinical characteristics related to pulmonary arterial hypertension in Algeria.
• Conducted genetic analysis in an Algerian population
• Assessed clinical phenotypes of patients
• Limited by modest sample size and lack of family data
• Identified variants of unknown significance (VUS) related to pulmonary arterial hypertension
• Assessment of heritability was constrained due to sample size
• Clinical characteristics showed variability among individuals

Abstract