Cysteine and viscosity double-locked responsive fluorescent probe for imaging in HeLa cells

Key Points

• This research aims to develop a fluorescent probe that can sense changes in cysteine levels and cellular viscosity in HeLa cells.
• Developed a dual-responsive fluorescent probe for cysteine and viscosity.
• Evaluated the probe's imaging capabilities in HeLa cells.
• Analyzed the effects of the tumor microenvironment on probe responsiveness.
• The probe effectively detected fluctuations in cysteine levels (p<0.01).
• Imaging showed significant changes in cellular viscosity in tumor microenvironments (p<0.05).
• Enhanced imaging clarity indicated the probe's potential for real-time monitoring.

Abstract