What question did this study set out to answer?

Evaluate the role of thermoresponsive hydrogels in controlled drug delivery to the back of the eye.

April 29, 2026Open Access

Thermoresponsive hydrogels for controlled drug delivery to the back of the eye: a data-driven guide to formulation design

Key Points

Evaluate the role of thermoresponsive hydrogels in controlled drug delivery to the back of the eye.
Assessment of polymer composition
Analysis of mechanical properties and safety
Evaluation of drug release characteristics
Identified key factors influencing mechanical properties of hydrogels
Demonstrated safety profiles of various formulations
Provided guidelines for optimizing formulation design based on therapeutic class

Abstract

This study comprehensively evaluates intravitreal thermoresponsive, drug-loaded hydrogels, highlighting how polymer composition and therapeutic class influence mechanical properties, safety, and release to guide rational formulation design.

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Authors

Alexa K. Beathard-Wojan

Vibhuti Agrahari

Journals

Biomaterials Science

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Institutions

University of Oklahoma Health Sciences Center

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Building similarity graph...

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Thermoresponsive hydrogels for controlled drug delivery to the back of the eye: a data-driven guide to formulation design

Key Points

Abstract

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Discussion

Authors

Journals

Actions

Institutions

References and Citations

Citation Network

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Discussion

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