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April 29, 2026Open Access

Evaluating acridones as novel therapeutics for human babesiosis

Puntos clave

This research aims to evaluate the effectiveness of acridones as novel therapeutics for human babesiosis.
Assessment of acridones for antibabesial activity
Analysis of pharmacokinetic properties of acridones
Exploration of combination regimens for treatment
Acridones demonstrate significant antibabesial activity
Potential lead chemotypes for therapeutic development identified
Further studies needed for optimizing pharmacokinetic properties

Resumen

antibabesial activity and represent promising lead chemotypes for therapeutic development. To advance these candidates, future studies focused on optimizing their pharmacokinetic properties and evaluating synergistic combination regimens will be essential for progressing toward effective treatments for human babesiosis.

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Authors

P

Pratap Vydyam

E

Elizabeth Zhang

A

Anasuya C. Pal

Journals

Antimicrobial Agents and Chemotherapy

Actions

Institutions

Yale University

Portland State University

References and Citations

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Evaluating acridones as novel therapeutics for human babesiosis | Synapse

Cite this study

Vydyam et al. (Mon,) studied this question.

www.synapsesocial.com/papers/69f154e0879cb923c4945299 — DOI: https://doi.org/10.1128/aac.00016-26