Lemierre Syndrome Complicated by Cervicofacial Necrotizing Infection – Case Report

Background: Lemierre syndrome is a rare but potentially fatal condition characterized by septic thrombophlebitis of the internal jugular vein, most commonly following an oropharyngeal infection caused by Fusobacterium necrophorum. Case presentation: We report the case of a 34-year-old previously healthy patient who presented with severe sepsis following an untreated pharyngitis. The clinical course was complicated by cervicofacial necrotizing fasciitis, internal jugular vein thrombosis, and septic pulmonary emboli. Management and outcome: The patient required emergency surgical intervention with extensive debridement and drainage, broad-spectrum antibiotic therapy, anticoagulation, and intensive supportive care. Conclusions: Early recognition, aggressive surgical management, and multidisciplinary care are essential to improve outcomes in severe forms of Lemierre syndrome.