Mesenchymal stem cell-derived conditioned medium demonstrates novel antibacterial effects in ocular bacterial infections.

Key Points

• The research aims to evaluate the antibacterial effects of conditioned medium from mesenchymal stem cells on ocular bacterial infections.
• Utilized a human corneal infection model.
• Administered adipose-derived MSC-CM compared to untreated controls.
• Assessed bacterial burden and corneal transparency outcomes.
• Adipose-derived MSC-CM significantly decreased bacterial burden compared to controls.
• Corneal transparency was preserved in the MSC-CM treated group, unlike untreated controls.

Abstract