Analyzing high-dimensional neuroimaging data for disease classification is challenged by spatial misalignment across subjects. We propose a cyclic-shift logistic sparse Kronecker product decomposition (CS-SKPD) model that embeds a shift-aware mechanism into a low-rank tensor regression framework. By generating adaptively aligned views of the input, the model improves robustness to anatomical variability while preserving interpretability through sparse spatial factorization. Theoretical analysis establishes asymptotic consistency under a restricted strong convexity condition adapted to logistic loss. Simulation studies demonstrate accurate signal recovery under noise and misalignment, with favorable trade-offs between resolution and efficiency. Applied to the Open Access Series of Imaging Studies (OASIS)-1 and Alzheimer’s Disease Neuroimaging Initiative (ADNI)-1 MRI data, the model attains competitive classification performance and identifies clinically relevant regions, such as the hippocampus and cerebellum.
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Hsin-Hsiung Huang
Yuh-Haur Chen
Teng Zhang
Statistics and Computing
University of Central Florida
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Huang et al. (Tue,) studied this question.
www.synapsesocial.com/papers/69fbefd5164b5133a91a3e4f — DOI: https://doi.org/10.1007/s11222-026-10892-y