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May 7, 2026

Study on Preparation and Pharmacokinetics of Gentiopicroside Sustained Release Preparation

Puntos clave

This research aims to evaluate the preparation and pharmacokinetics of gentiopicroside sustained release formulations.
Developed two sustained-release formulations of gentiopicroside (GPS-MRT and GPS-MPOP).
Compared pharmacokinetics and bioavailability of these formulations with reference preparations.
GPS-MRT had a relative bioavailability of 103.24% and GPS-MPOP had 116.47%.
Both formulations prolonged drug release and reduced plasma concentration fluctuations.

Resumen

< 0.0001) h, respectively. Compared with reference preparations, the relative bioavailability was 103.24% for GPS-MRT and 116.47% for GPS-MPOP, respectively. Both of the two sustained-release preparations prolonged drug release and reduced plasma concentration fluctuation, which provides a new strategy for clinical application of GPS.

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Authors

Yanyan Guo

Lingyu YAO

Yonghui Duan

Journals

Pharmaceutical Development and Technology

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Institutions

Beijing University of Chinese Medicine

Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine

Qinghai Tibetan Hospital

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Building similarity graph...

Analyzing shared references across papers

Study on Preparation and Pharmacokinetics of Gentiopicroside Sustained Release Preparation

Puntos clave

Resumen

Citation Network

Connected Papers

Discussion

Authors

Journals

Actions

Institutions

References and Citations

Citation Network

Connected Papers

Discussion

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