A resected adrenocortical oncocytoma in a 59-year-old woman exhibited benign features and lacked uniform mitochondria, suggesting characteristics more similar to an adrenal cortical adenoma.
Case Report
No
59-year-old Japanese woman with a right adrenal mass (adrenocortical oncocytoma)
Resection and pathological, immunohistochemical, and ultrastructural examination
Pathological and biological features of the tumor
Adrenocortical oncocytoma exhibits distinct biological and ultrastructural features from renal oncocytoma, sharing more characteristics with adrenal cortical adenoma.
Adrenocortical oncocytoma is a rare adrenal tumor. We report a 59-year-old Japanese woman with a right adrenal mass. The resected specimen showed a well-defined, mahogany-brown tumor measuring 4.3 cm. Microscopically, the tumor scored 0 under both the Lin-Weiss-Bisceglia system and the reticulin algorithm, indicating benignity. Immunohistochemical analysis revealed that tumor cells were positive for mitochondria and negative for BSND and ATP6V1G3. Ultrastructural examination found no uniform mitochondria in the cytoplasm of the tumor cells. The oncocytoma in this case may share more characteristics with an adrenal cortical adenoma than with a renal oncocytoma.
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Mitsuhiro Tachibana
Hiromichi Nakagawa
Hayato Nozawa
Urology Case Reports
Shizuoka Medical Center
Shimada Municipal Hospital
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Tachibana et al. (Fri,) conducted a case report in Adrenocortical oncocytoma (n=1). Tumor resection was evaluated. A resected adrenocortical oncocytoma in a 59-year-old woman exhibited benign features and lacked uniform mitochondria, suggesting characteristics more similar to an adrenal cortical adenoma.
www.synapsesocial.com/papers/69fd7cd4bfa21ec5bbf05be0 — DOI: https://doi.org/10.1016/j.eucr.2026.103465
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