Phytocomponents Derived From Naturally Growing Chamaedorea seifrizii as Novel α‐Amylase Inhibitors for Diabetes Management: In Vitro and In Silico Approach

. According to the results of the in silico ADMET analysis, all the ligand molecules showed good absorption and did not cause any harmful effects. In a kinetic study, CIAE and CFAE were found to inhibit α-amylase in a noncompetitive way. To best of our knowledge, this is first time study reporting bioactive chemicals from C. seifrizii extracts exhibiting anti-α-amylase potential. To validate these results, more studies utilizing clinical trials and animal models are required. This study claimed that due to richness of phytocompounds, C. seifrizii extracts may help to block the enzyme α-amylase, which leads to the creation of new drugs for diabetes.