Key points are not available for this paper at this time.
BACKGROUND: camera to detect differences in keloid features pre- and post-steroid injection. In order to identify whether those variation could be considered as treatment response predicting factors. METHODS: Enrolled patients received three intra-lesional steroid injections at four-weekly intervals. Images were taken with the Antera 3D camera 12 and 24 weeks after treatment. Keloids' colour, volume, and area as well as haemoglobin and melanin average levels and variation have been analysed pre- and post-steroid injection. t Tests and relative risk have been used to analyse the significance and association strength of our finding. RESULTS: Forty patients have been enrolled in the study. Significant changes as been recorded in keloids' volume and colour after steroid injection (P < 0.05). 53% have recorded a Hb reduction showing no recurrence of pathology, patient who had increase in Hb showed an early recurrence. Melanin variation was significant after steroid injection (P < 0.05) but no correlation has been found with treatment response. CONCLUSIONS: The Antera 3D camera is able to detect differences in the investigated keloid's features helping in two ways: by providing an objective, longitudinal method to monitor and document changes in scar morphology, and through monitoring haemoglobin change, which strongly correlates to both response to treatment and likelihood of recurrence. Allowing clinicians to identify which patients will respond early, in order to change treatment if necessary, limiting morbidity and costs.
Building similarity graph...
Analyzing shared references across papers
Loading...
Francesca Ruccia
Giovanni Zoccali
Lilli Cooper
Skin Research and Technology
University of Brighton
Queen Victoria Hospital
Queen Victoria Hospital NHS Foundation Trust
Building similarity graph...
Analyzing shared references across papers
Loading...
Ruccia et al. (Tue,) studied this question.
www.synapsesocial.com/papers/6a04c46a8d238486f0ad3c2b — DOI: https://doi.org/10.1111/srt.13050
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: